METABOLISM AND MUTAGENICITY OF SOURCE WATER , 1,3-DCP and 2,2-DCP To give some insight into the mechanistic basis of P450 and GST metabolism, several other haloalkanes also were examined in the same system To assess the potential for mutagenicity, 1,3-DCP and 2,2-DCP were evaluated in theSalmonella plate-incorporation assay in the presence or absence of rat liver …