Aug 15, 2017· 2.2. Thrombolysis. Since the publication the National Institute of Neurological Diseases Stroke (NINDS) trial in 1995 [], intravenous thrombolysis using alteplase has become an important part of hyperacute stroke treatment.The initial licence was restricted to patients under the age of 80 years, as older patients were excluded from trials assessing thrombolysis.
